Arthritis

Study findings from D.D. Orielly et al broaden understanding of arthritis

Published in Pharma Law Weekly, July 21st, 2009

According to recent research published in the Pharmacogenomics Journal, "Although tumor necrosis factor-alpha (TNF-alpha) blockade is a very effective therapy for rheumatoid arthritis (RA), not all patients achieve a favorable outcome. The objective of this study was to determine if the common TNF-alpha variant -308(A) predicts poor response to TNF-alpha inhibitors in RA patients using meta-analysis."

"Studies were identified using MEDLINE and EMBASE. Data were extracted based on DAS28 or achieving at least American College of Rheumatology 20 response. A total of nine studies met the inclusion criteria representing a total of 692 RA patients. There was no...

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Source: Pharma Law Weekly (2009-07-21)

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