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Pharmacokinetics

Researchers at Central South University have published new data on pharmacokinetics

Published in Pharma Law Weekly, August 11th, 2009

"Duloxetine hydrochloride is a balanced selective serotonin and norepinephrine reuptake inhibitor. Despite being widely used for the treatment of major depressive disorder in China, little information is available on the pharmacokinetic (PK) properties of duloxetine in Chinese subjects," scientists writing in the journal Clinical Therapeutics report.

"This study was designed to determine the concentration of duloxetine in human plasma and to compare the PK properties of duloxetine after administration of single and multiple doses of duloxetine in healthy Chinese volunteers. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for determining the...

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