Hyperplasia

New findings in hyperplasia described from National Institutes of Health

Published in Pharma Law Weekly, September 22nd, 2009

According to recent research from the United States, "ACTH-independent macronodular adrenal hyperplasia (AIMAH) is often associated with subclinical cortisol secretion or atypical Cushing's syndrome (CS). We characterized a large series of patients of AIMAH and compared them with patients with other adrenocortical tumors."

"We recruited 82 subjects with: 1) AIMAH (n = 16); 2) adrenocortical cortisol-producing adenoma with CS (n = 15); 3) aldosterone-producing adenoma (n = 19); and 4) single adenomas with clinically nonsignificant cortisol secretion (n = 32). Urinary free cortisol (UFC) and 17-hydroxycorticosteroid (17OHS) were collected at baseline and during...

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Source: Pharma Law Weekly (2009-09-22)

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