Published in Pharma Law Weekly, September 22nd, 2009
"If clopidogrel given crushed via NG tube provides faster absorption, it could allow earlier clopidogrel loading. Nine healthy human subjects (34.7 +/- 11.1 years, 5 males) were given 300 mg clopidogrel in crushed form via NG tube with 30 mL water after 8 hours of fasting. Plasma levels of the primary circulating inactive clopidogrel metabolite SR26334 were measured after 20 minutes, 40 minutes,...
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