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Research from R.W. Platt and co-authors reveals new findings on life sciences

Published in Pharma Law Weekly, September 22nd, 2009

Current study results from the report, 'Time-modified confounding,' have been published. "According to the authors, time-modified confounding occurs when the causal relation between a time-fixed or time-varying confounder and the treatment or outcome changes over time. A key difference between previously described time-varying confounding and the proposed time-modified confounding is that, in the former, the values of the confounding variable change over time while, in the latter, the effects of the confounder change over time," researchers in Montreal, Canada report.

"Using marginal structural models, the authors propose an approach to account for time-modified...

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