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Cardioprotection

New findings reported from University of British Columbia describe advances in cardioprotection

Published in Pharma Law Weekly, October 6th, 2009

"Propofol concentrations that produce laboratory-based cardioprotective effects are generally greater than those produced under routine anesthesia during cardiac surgery. It is unknown whether experimental cardioprotective propofol concentrations can routinely be achieved during cardiopulmonary bypass (CPB) using continuous infusion," scientists writing in the Canadian Journal of Anaesthesia - Journal Canadien D Anesthesie report.

"Twenty-four patients scheduled for primary aortocoronary bypass grafting with CPB were allocated to receive one of three propofol infusion rates; 50, 100, or 150 mu g center dot A kg(-1) center dot A min(-1) in an open-label pilot...

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