Published in Pharma Law Weekly, November 10th, 2009
"Different monocyte subsets, which differentially contribute to plaque infiltration and to atherosclerosis complications, have been identified. Similarly, depending on different environmental signals plaque-associated macrophages can express polarized pro- and antiatherogenic programs by influencing lipid metabolism, inflammatory responses, and plaque stability," wrote A. Mantovani and colleagues, Humanitas Clinical Institute.
The researchers concluded: "Thus, a "macrophage...
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