Gene Therapy

Studies in the area of gene therapy reported from B. Lei and co-researchers

Published in Pharma Law Weekly, November 10th, 2009

According to recent research from Chongqing, People's Republic of China, "Adeno-associated virus serotype-9 (AAV-9) is a promising gene delivery vector. In this study, we evaluated AAV-9 transduction in the mouse retina."

"Three different AAV vectors were used in our study: AAV-9.RSV.AP, AAV-9.CMV.eGFP, and AAV-9.CMV.Delta R4-23/Delta C. In these vectors, two different promoters (the cytomegalovirus promoter-CMV promoter and the Rous sarcoma virus-RSV promoter) were used to express three different transgenes including the alkaline phosphatase (AP) gene, the enhanced green fluorescent protein (eGFP) gene, and a therapeutic microdystrophin gene (the Delta R4-23/Delta C)....

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Source: Pharma Law Weekly (2009-11-10)

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