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Hyperhomocysteinemia

Studies in the area of hyperhomocysteinemia reported from K. Ukinc and co-researchers

Published in Pharma Law Weekly, November 24th, 2009

"Hyperhomocysteinemia is a well-defined risk factor for endothelial dysfunction and atherosclerosis. A point mutation (677 C-T) of MTHFR gene results in a significant increase at plasma homocysteine levels," scientists writing in the journal Endocrine report.

"In this study we aimed to evaluate the effects of MTHFR gene mutation and consequent hyperhomocysteinemia on the development of diabetic microvascular complications in comparison with the other defined risk factors. Diabetic patients without a history of macrovascular complication or overt nephropathy enrolled into the study. The presence of MTHFR 677 C-T point mutation was evaluated by Real-Time PCR...

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