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Wellcome Trust Sanger Institute

Lung cancer and melanoma laid bare

Published in Pharma Law Weekly, December 29th, 2009

Research teams led by the Wellcome Trust Sanger Institute announce the first comprehensive analyses of cancer genomes.

All cancers are caused by mutations in the DNA of cancer cells which are acquired during a person's lifetime. The studies, of a malignant melanoma and a lung cancer, reveal for the first time essentially all the mutations in the genomes of two cancers.

Lung cancer causes around one million deaths worldwide each year: almost all are associated with smoking. The number of mutations found suggest that a typical smoker would acquire one mutation for every 15 cigarettes smoked.

Although malignant melanoma comprises...

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