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Massachusetts General Hospital

Risedronate improves bone density in females with anorexia nervosa

Published in Physician Business Week, October 12th, 2004

Risedronate improves bone density in females with anorexia nervosa, study results show.

"Anorexia nervosa (AN), a psychiatric disease characterized by chronic starvation, is complicated by severe bone loss, for which there is no effective, available therapy. Although bone resorption is markedly increased in these patients, estrogen is an ineffective anti-resorptive therapy in the setting of undernutrition," wrote K.K. Miller and colleagues, Massachusetts General Hospital.

The researchers "hypothesized bisphosphonate administration would result in a decrease in bone resorption and an increase in bone density in women with AN and bone loss, despite...

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