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Addiction Medicine

Researchers from Harvard University publish new studies and findings in the area of addiction medicine

Published in Physician Business Week, January 16th, 2007

A new study, "Opioids for chronic nonterminal pain," is now available. According to recent research from the United States, "This article first reviews the evidence for and against chronic opioid therapy. Evidence supporting the opioid responsiveness of chronic pain, including neuropathic pain, includes multiple randomized trials conducted over months (up to 8 months)."

"Observational studies are conducted for longer, and many also support opioid analgesic efficacy. Concerns have arisen about loss of efficacy with prolonged use, possibly related to tolerance or opioid-induced hyperalgesia. Mechanisms of tolerance and opioid-induced hyperalgesia are explored. Evidence on...

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