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Dietary lignins are precursors of murine lignans

Published in Physician Law Weekly, March 10th, 2004

Dietary lignins play a key role in the production of lignans in rats.

"The mammalian lignans enterolactone (ENL) and enterodiol, commonly found in human plasma and urine, are phytoestrogens that may contribute to the prevention of breast cancer and coronary heart disease," nutritionists in France explained. "They are formed by the conversion of dietary precursors such as secoisolariciresinol and matairesinol lignans by the colonic microflora."

In a recent study, A.N. Begum and colleagues at the National Institute of Agronomy Research (INRA) identified "lignins, cell-wall polymers structurally related to lignans, as precursors of mammalian...

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