German Federal Research Center for Nutrition
Pressure treatment reduces infectivity of prions
Published in Physician Law Weekly, April 7th, 2004
"High hydrostatic pressure is a mild technology compared with high temperatures and is commonly used for food pasteurization. Crude brain homogenates of terminally diseased hamsters infected with scrapie 263K strain were heated at 60 degrees C and/or pressurized up to 1000 MPa for 2 hours. Prion proteins were analyzed for their proteinase K sensitivity using a Western blot technique," researchers in Germany report.
"PrPsc pressurized with 500 MPa or above proved to be proteinase K sensitive," stated Avelina Fernandez Garcia and collaborators at the...
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Source: Physician Law Weekly (2004-04-07)
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