University of North Carolina
Novel PCR assay enables norovirus genotyping
Published in Physician Law Weekly, April 21st, 2004
NoV, "previously called 'Norwalk-like viruses', have emerged as the single most important cause of acute gastroenteritis worldwide," virologists in the United States explained. "Most diagnostic reverse transcription-polymerase chain reaction (RT-PCR) assays target the viral RNA-dependent RNA polymerase; however, the major capsid protein (VP1) is the reference genomic region for establishing genotypes."
In their study, J. Vinje and colleagues at the University of North Carolina "analyzed complete NoV VP1 sequences (n=100) and determined a region (region D) that was most suitable to...
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Source: Physician Law Weekly (2004-04-21)
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