Carnegie Mellon University

Fibroblast growth and protein kinase inhibitor monitored by microimpedance

Published in Physician Law Weekly, September 8th, 2004

Fibroblast growth and H-7 protein kinase inhibitor response are being monitored in microimpedance sensor arrays.

"Functional genomic studies and drug candidate testing both require high throughput, parallel experimentation strategies to screen for variable cellular behaviors. ...[W]e describe the use of an impedance-sensing electrode array that is capable of sensing cell 'presence' as well as the extent of cell (focal) attachment to the substrate." researchers in the United States report.

D.D. Nguyen and colleagues of Carnegie Mellon University wrote, "The signals provided by mouse fibroblasts on a sensing structure containing four different sized...

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Source: Physician Law Weekly (2004-09-08)

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