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University of Queensland

Ethical issues regarding cocaine vaccine outlined

Published in Physician Law Weekly, October 13th, 2004

Researchers outline the ethical issue in using a cocaine vaccine to treat and prevent cocaine abuse and dependence in a recent issue of the Journal of Medical Ethics.

According to recent research from Australia, "A 'cocaine vaccine' is a promising immunotherapeutic approach to treating cocaine dependence which induces the immune system to form antibodies that prevent cocaine from crossing the blood brain barrier to act on receptor sites in the brain. Studies in rats show that cocaine antibodies block cocaine from reaching the brain and prevent the reinstatement of cocaine self-administration. A successful phase 1 trial of a human cocaine vaccine has been...

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