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University of Bologna

Anti-inflammatory compounds in middle age may decrease CV events in aging

Published in Physician Law Weekly, December 8th, 2004

Results from a pilot study describe the concomitant presence of polymorphic alleles of interleukin-1 beta, interleukin-6 and apolipoprotein E is associated with an increased risk of myocardial infarction in elderly men.

Investigators in Italy report, "Genetic background of inflammatory or anti-inflammatory molecules may be helpful in identifying subjects with increased or decrease risk of developing cardiovascular disease. Bi-allele polymorphism (C>T) in the promoter region (-511) of the interleukin-1beta (IL-1beta) gene and the bi-allele polymorphism (G>C) in the promoter region (-174) of interleukin-6 (IL-6) gene were determined in elderly men patients with...

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