St. Jude Children's Research Hospital

Pattern of gene expression linked to multiple-drug resistance of leukemic cells

Published in Physician Law Weekly, May 18th, 2005

The discovery of a specific pattern of gene expression linked to multiple-drug resistance of leukemic cells is giving researchers crucial information into why standard therapies fail to cure some children with acute lymphoblastic leukemia (ALL).

This finding, from investigators at St. Jude Children's Research Hospital, could lead to development of drugs that would overcome that resistance.

This new finding helps to explain why about 20% of children with ALL, the most common form of childhood cancer, are not cured with the same drug therapy that cures the remaining 80% of children with this disease. A report on the study that produced this new...

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Source: Physician Law Weekly (2005-05-18)

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