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University of Insubria

Combination therapy improved plasma lipids in diabetic patients

Published in Physician Law Weekly, May 25th, 2005

Combination therapy (enalapril plus valsartan) in patients with diabetes and hypertension resulted in improvements in plasma lipids during renin-angiotensin system blockade.

According to published research from Italy, "There is experimental evidence of an interaction between the angiotensin system and lipid metabolism. The aim of this study was to evaluate whether a block of the angiotensin system achieved both by ACE inhibition and angiotensin II-ATl receptor blockade could affect the plasma lipid profile and, if so, what relationship exists between these possible changes and glucose metabolism and blood pressure. In 50 patients with type 2 diabetes and hypertension,...

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