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Physician Law Weekly

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Bellevue Hospital, St. Etienne



Target-controlled infusion improves propofol's hemodynamic effects



June 22nd, 2005

A recent report provides a comparison of target- and manually-controlled infusion propofol and etomidate/desflurane anesthesia in elderly patients undergoing hip fracture surgery.

Investigators in France report, "Elderly patients have a higher risk of developing adverse drug reactions during anesthesia, especially anesthesia affecting cardiovascular performance. In [our] prospective randomized study we compared quality of induction, hemodynamics, and recovery in elderly patients scheduled for hip fracture surgery and receiving either etomidate/desflurane (ETO/DES) or target-controlled (TCI) or manually controlled (MAN) propofol infusion for anesthesia."

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Source: Physician Law Weekly (2005-06-22)

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