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Baker Heart Research Institute, Melbourne

Agents in development for treatment of diabetic nephropathy reviewed

According to a study from Australia, "Diabetic nephropathy is a leading cause of end-stage renal disease, and accounts for significant morbidity and mortality in patients with diabetes. Diabetic nephropathy seems to occur as a result of an interaction between metabolic and hemodynamic factors, which activate common pathways that lead to renal damage. In the past, the treatment of diabetic nephropathy has focused on the control of hyperglycemia. Newer targets, some of which are linked to glucose-dependent pathways, appear...

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