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Johns Hopkins University

Vitamin D repletion regimen for CF patients did not work

Published in Physician Law Weekly, August 3rd, 2005

The recently published vitamin D repletion regimen suggested by the Cystic Fibrosis Foundation's Consensus Panel on Bone Health for replacing the vitamin in cystic fibrosis (CF) patients has been called by researchers who tested it "strikingly ineffective."

Out of 66 adults with CF, only 5 patients who had been treated with 50,000 IU of the vitamin per week for 8 weeks had their serum levels corrected to the recommended degree, said the Johns Hopkins researchers.

The study was designed to determine the%age of adults with CF who required the recommended vitamin D repletion therapy because of serum levels below 30 nanograms per milliliter (30 ng/ml);...

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