Published in Physician Law Weekly, October 12th, 2005
"IsCT-P (ILKKIWKPIKKLF-NH2) is a novel alpha-helical antimicrobial peptide with bacterial cell selectivity designed from a scorpion-derived peptide IsCT. To investigate the role of L- or D-Pro kink on the structure and the mode of action of a short alpha-helical antimicrobial peptide with bacterial cell selectivity, we synthesized IsCT p, in which D-Pro is substituted for L-Pro(8) of IsCT-P," wrote S.S. Lim and colleagues, Chosun University.
"CD spectra revealed that...
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