Royal Free University College, London

HIV/TB coinfected donors have increased IL-4 and IFN-gamma in whole blood and lung lavage fluid

Published in Physician Law Weekly, January 4th, 2006

HIV/tuberculosis coinfected donors have increased interleukin-4 and interferon gamma in whole blood and lung lavage fluid.

According to a study from England, "Correcting the Th2 shift in HIV/AIDS represents a potential intervention strategy. However data on interleukin (IL)-4 expression in HIV or AIDS are uninterpretable because of failure to distinguish between IL-4 and its splice variant and natural antagonist, IL-4 delta 2.

"To determine Th1 [interferon (IFN)-gamma], IL-4 delta 2 and Th2 (IL-4) expression in whole blood and lung lavage from healthy volunteers and in HIV or HIV-tuberculosis (TB) coinfection," investigators conducted a...

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Source: Physician Law Weekly (2006-01-04)

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