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Osaka University

MAP3K7IP2/SUMO4 locus in IDDM5 interval is related to type 1 diabetes in Asian populations

Published in Physician Law Weekly, February 1st, 2006

The MAP3K7IP2/SUMO4 locus in the IDDM5 interval is related to type 1 diabetes in Asian populations.

"Association studies are a potentially powerful approach to identifying susceptibility variants for common multifactorial diseases such as type 1 diabetes, but the results are not always consistently reproducible. The IDDM5 locus has recently been narrowed to an approximately 200-kb interval on chromosome 6q25 by two independent groups," investigators in Japan report.

S. Noso and colleagues with Osaka University remarked, "These studies demonstrated that alleles at markers in the mitogen-activating protein kinase 7 interacting protein 2...

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