Washington University, St. Louis
PI ability to impair glucose disposal correlates with degree of insulin resistance
Published in Physician Law Weekly, February 1st, 2006
According to recent research from the United States, "The clinical use of HIV protease inhibitors (PIs) is associated with the development of peripheral insulin resistance. The incidence and degree of impaired glucose tolerance observed in treated patients vary considerably between drugs, however."
"To compare the ability of HIV PIs to alter peripheral glucose disposal acutely in a genetically identical model system at therapeutically relevant drug levels, healthy lean mate rats previously...
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Source: Physician Law Weekly (2006-02-01)
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