Physician Law Weekly

Mergers & Acquisitions - BioScrip acquires Intravenous Therapy Services

Midwestern University, Downers Grove - System B^0,+ regulation of developmental processes may raise metabolic syndrome and obesity risk

Mie University - HCV immune-complex dynamics predict response to therapy

Mount Sinai School of Medicine, New York - Stem cell attraction to their niche related by sympathetic nervous system

Myogen, Inc. - Ambrisentan ARIES-2 data to be presented at Thoracic Society meeting

Myogen, Inc. - GlaxoSmithKline and Myogen announce pulmonary arterial hypertension partnership

Myogen, Inc. - Myogen reports net loss of $63 million or $1.68 per share for 2005

NIH/National Institute of Mental Health - Depression model leaves mice with molecular scar

Nabi Biopharmaceuticals - Nabi Biopharmaceuticals announces U.S. fast track designation for NicVax

Nanjing University - Antitumor responses are elicited by low dose of live tumor cells

National Cancer Center, Chiba - Arctigenin identified as an antitumor agent

National Center for Scientific Research Demokritos, Athens - Tc-99m-labeled bombesin-like peptides examined for use in early cancer detection

National Comprehensive Cancer Network - NCCN announces important updates to Myelodysplastic Syndromes Clinical Practice Guidelines

National Comprehensive Cancer Network - National Comprehensive Cancer Network updates kidney cancer clinical practice guidelines

National Development & Research Institutes, Inc. - Scientific study of recovery process sheds new light on role of spirituality

National Institute of Health, Seoul - Mupirocin-resistant Staphylococcus aureus is clonally transferred in long-term care facilities

National Institute of Molecular Genetics, Milan - Studies add new findings to hepatitis C virus body of knowledge

National Quality Forum - Three prominent healthcare leaders join NQF board of directors

National University of Singapore - Mitochondria proposed as target for cancer therapy

Netherlands Institute of Health Services Research - Influenza vaccine refusal reasons among high-risk persons in Europe are reported

Neurogen Corporation - Neurogen Corporation announces $10.6 million net loss for the fourth quarter of 2005

Neuromed Pharmaceuticals Ltd. - Neuromed raises US$25 million, completing fourth-round private equity financing

NicOx S.A - NicOx compound demonstrates good preclinical results in Pfizer glaucoma collaboration

Niigata University - Prognosis of glioma linked to increased expression of CCAAT/enhancer binding protein 6

Noguchi Institute, Tokyo - Calcitonin derivatives can be predictably produced through glycosylation

North Dakota State University - DNA vaccine is targeted to skin with the use of electroporation

North Shore-Long Island Jewish Health System - New York hospital launches Patient Safety Institute with simulation lab

Northwestern University Feinberg School of Medicine, Chicago - Polycystic ovary syndrome in adolescent girls may increase the incidence of metabolic syndrome

Northwestern University, Chicago - Researchers use embryonic model to reprogram malignant melanoma

NovaDel Pharma Inc. - NovaDel announces completion of clinical trials for Zensana oral spray for chemotherapy patients

Novogen, Ltd. - Novogen IBD drug phase I clinical trial shows promise

NutraCea - NutraCea names Kody Newland as senior vice president of sales

Nuvo Research Inc. - Nuvo announces Pennsaid data reviewing four trials was published in the Journal of Rheumatology

Oculus Innovative Sciences - Oculus Innovative Sciences receives FDA clearance for OTC marketing of Dermacyn Wound Care

Ohio State University - A mucoadhesive hydrogel may serve as a drug delivery device to the mucosal epithelium

Ohio State University - Rotavirus vaccine development is aided by cytokine response analysis

Okayama University - Feasibility of using MR angiography without contrast examined in bone and soft tissue tumors

Okayama University Graduate School of Medicine - Findings describe new data in drug development research

Open Biosystems, Inc. - Open Biosystems signs Northwestern University to Open Access RNAi program

Oragenics, Inc. - Oragenics completes $600,000 financing

Oral Health - Children's health insurance program impacts access to dental care, study shows

Orexigen Therapeutics, Inc. - Orexigen Therapeutics appoints Dr. Gary Tollefson as CEO

Osaka University - Cholangiocellular carcinoma clinicopathology is not linked to angiogenesis factors

Osaka University - Chronic hepatitis B virus replication utilizes covalently closed circular DNA

PDL BioPharma, Inc. - PDL BioPharma names Andrew Guggenhime as senior vice president and chief financial officer

Pain Management - SpineMED decompression table rehydrates spinal discs to relieve pain

Patient Care - Hill-Rom hospital beds are in compliance with new U.S. FDA guidelines

Paul Ehrlich Institute, Langen - Kinase insert domain-containing receptor draws cytotoxic cells to tumor vessels

Pecs University - Traumatic axonal injury reviewed

Peking Union Medical College - HPV-16 fusion protein vaccine possesses therapeutic effects in animal model

Pennsylvania State University - School lunch involvement linked to free and reduced-price meals and banning fast foods

Personnel - Cigna HealthCare of Texas appoints James Saad as VP of sales

Personnel - Gentiva announces new executive appointments and promotion of CFO

Personnel - Glenn Sblendorio named executive vice president and CFO of The Medicines Company

Personnel - Lisa Harper, Gymboree chairman, elected to board of directors of Longs Drug Stores

Personnel - Nephros appoints Mark W. Lerner as chief financial officer

Personnel - Omnicell promotes Renee Luhr to vice president of sales

Personnel - Phase III Medical appoints Larry May as chief financial officer

Pharmaceutical Research - New report analyzes pharmaceutical managed markets trends, strategies, and resources

Pharmacyclics, Inc. - Pharmacyclics appoints Geoffrey Cooper, PhD, as senior vice president, business development

Pharmazeutisches Institute, Tubingen - Recent findings illuminate research in HIV/AIDS HAART

Phoenix Data Systems - Phoenix Data Systems introduces interactive voice response solutions

Plethora Solutions - Plethora receives IND approval of Phase II Clinical Trial with PSD597

Pluristem Life Systems, Inc. - Pluristem refocuses business strategy to development of cell therapy products

Point Therapeutics, Inc. - Point Therapeutics' PT-630 demonstrates improved glucose regulation and metabolic parameters

Policlinico S Orsola, Bologna - Roles of MR imaging and M angiography in congenital diseases of thoracic aorta are considered

Private University of Witten Herdecke - New findings in herpesvirus described

Professional Education - Stottler Henke to develop intelligent tutoring systems to train healthcare professionals

Prostate Cancer - Benefit of prostate-specific antigen testing surveyed among men at risk for prostate carcinoma

Proteome Systems, Ltd. - Proteome Systems Limited announces 60.6% increase in revenue for the half year

Quality Assurance - CPP helps St. Luke's Hospital improve patient satisfaction

Quality of Life - Public says treatment decisions should rest with patients and physicians, NCL survey finds

Radiological Society of North America - MRI rules out acute appendicitis in pregnancy

Radiological Society of North America - Some breast lesions benign on needle biopsy show cancer when removed

Research & Markets - Positive factors are expected to help OTC healthcare in Ireland

Roche Palo Alto - Therapy using a nucleoside analog inhibits hepatitis C virus replication

Roche Pharmaceuticals - First 'World Kidney Day' calls for early detection and prevention of chronic kidney disease

Rockefeller University, New York - Hepatitis C virus is activated for low-pH-triggered cell entry

Roswell Park Cancer Institute, Buffalo - Melanoma-associated CTL response is enhanced by CD4 T cells in transgenic mice

Royal Brompton Hospital, London - Primary aortic co-arctation stenting shows excellent clinical, angiographic outcomes

Royal Free & University College London Medical School - GST gene variant is linked to elevated inflammation markers and lipid peroxidation in DM

Royal Melbourne Institute of Technology University - Elevated HSL Ser⁶⁶⁰ phosphorylation maintains HSL activity after AMPK activation

Ruhr Universitat, Bochum - Recent findings in cardiovascular disease provide new insights

Ruhr University of Bochum - Research in cardiology provides new insights

SUNY, Buffalo - Colorectal cancer rates do not appear affected by vitamin D and calcium supplements

SUNY, Buffalo - Ssa1 and Ssa2 proteins are required for Candida albicans fungicidal activity

Sahlgrenska University Hospital, Gothenburg - GH effect on 11beta HSD enzyme activity in abdominal obesity depends on treatment duration

Saint John's Mercy Medical Center, St. Louis - New research in the area of cardiology detailed

Saitama Cardiovascular & Pulmonology Center, Konan - Enhanced efficacy of propofol during cardiopulmonary bypass may be due to reduced plasma binding

Schering-Plough Corporation - Schering-Plough targets Europe, Latin America, Asia-Pacific with new appointments, actions

Schleswig-Holstein University Clinics, Lubeck - Arrhythmia pathogenesis may be linked to preproenkephalin gene expression in cardiac hypertrophy

Scripps Research Institute - Peptide vaccination of mice immune to LCMV or vaccinia virus causes serious pathology

Scripps Research Institute - Tumor angiogenesis may stall when treated with tRNA synthetase fragments

Second Affiliated Hospital, Hangzhou - Research add new data to leukemia body of knowledge

Semmelweis University, Budapest - Chromosome 3 abnormalities in acute myeloid leukemia patients analyzed with FISH

Seoul National University - Itraconazole has been formulated with improved dissolution and oral absorption

Sexual & Reproductive Health - Survey unveils disconnect in mother/daughter communication about menstruation

Shinshu University - Downregulation of LDL receptor expression by IL-1 beta alters cardiac lipid metabolism during sepsis

Siemens Medical Solutions - Siemens Medical introduces dual source computed tomography system

Signet Laboratories, Inc. - Signet, Bayer sign agreement to do research on urinary trypsin inhibitor immunoassays

Skejby University Hospital, Aarhus - HAART initiation and continuation hinders HIV 103N and 184V mutations alone or in tandem

Skinvisible, Inc. - Skinvisible's hand sanitizer launched in Canadian restaurant and hospitality markets

Smith & Nephew - Smith & Nephew appoints John Mullen vice president of U.S. sales for endoscopy division

Smith & Nephew - U.S. FDA approves label change to include physician dosing option for joint fluid therapy

SoLapharm, Inc. - SoLapharm raises $4 million in third financing round by sale of common stock

Sontra Medical Corporation - Sontra Medical completes financing with net proceeds of about $1.6 million

Southampton General Hospital - MUST predicts mortality and length of hospital stay in acutely ill elderly

Southern Medical University, Guangzhou - Method generates monoclonal antibodies against plasma proteins

Spectrum Pharmaceuticals, Inc. - Daniel Pertschuk, MD, named VP of medical affairs for Spectrum Pharmaceuticals

St. Antonius Hospital, Nieuwegein - Osteoarthritis patients respond well to non-pharmacological intervention

St. Elizabeth's Regional Burn & Wound Care Center, Lincoln - Collagen-glycosaminoglycan matrix feasible for chronic wound therapy

St. Vincent's University Hospital, Dublin - Lobular carcinoma patients at risk of compromised margins identified

Standard Management Corporation - Standard Management signs prime vendor distribution agreement with AmerisourceBergen

Stanford University - New findings in the area of obesity pathogenesis detailed

Stanford University - Researchers' findings advance disease associations research

Streck - Streck introduces nucleated red blood cell control for use with hematology analyzer

Sungkyunkwan University, Seoul - Adenoma diagnosis by CT alone may lead to misdiagnosis

Sunnybrook & Women's College Health Sciences Center, Toronto - Tumor immunity is enhanced by canary pox virus expressing melanoma antigen

Surgical Technology - Brigham and Women's Hospital initiates trial of SurgiCount's safety-sponge system

Swiss Institute for Experimental Cancer Research, Epalinges - Researchers' work adds to oncology body of knowledge

Sybron Dental Specialties, Inc. - Sybron Dental group wins top prizes at 2006 dental industry awards

TREK Diagnostic Systems - U.S. FDA grants clearance for TREK Diagnostic's anti-tubercular susceptibility agent

Taisho Pharmaceutical Co. - Atopic dermatitis-like model in mice determines parasitism of mites, not allergies, are the cause

Takeda Global Research & Development Center - Insomnia treatment by ramelteon had mild or moderate adverse reactions

Takeda Pharmaceutical Company, Ltd. - Takeda selects target for drug development in cardiovascular disease from Lexicon Genetics

Technical University of Munich - Detection of bone marrow lesions improved by ferumoxtran-10-enhanced MR imaging

Tel Aviv University - Parental occupational exposure linked to risk of acute lymphoblastic leukemia in offspring

Telzuit Medical Technologies, Inc. - Telzuit signs co-marketing, sales agreement with Cardiomedics for wireless monitor system

The Danish Medicines Agency - U.S. FDA web site warns of risk of cardiovascular adverse reactions from methylphenidate

The Immune Response Corporation - Immune Response Corporation completes $8 million private financing

ThermoGenesis Corp. - ThermoGenesis Corp. closes offering of common stock

Thoraxklinik Heidelberg - Researchers publish new studies and findings in the area of diagnostics

TissueLink Medical Inc. - TissueLink adds Rick Randall, J. Neal Armstrong, Win Wallin as independent board members

Tokyo Medical & Dental University - HCV replication is affected divergently by interferon-alpha subtypes

Tulane University, New Orleans - Glycemic control does not impact nontraditional cardiovascular disease risk factors equally

Tulane University, New Orleans - New research in the area of imaging detailed

Turku University - hs-CRP was an independent risk factor for coronary heart disease deaths in type 2 diabetics

U.S. Centers for Disease Control & Prevention -  Streptococcus pneumoniae serotypes can be identified by new PCR method

U.S. Centers for Disease Control & Prevention - Pediatric vaccine stockpile program in U.S. is described

U.S. Centers for Disease Control & Prevention - Respiratory disease outbreaks in nursing homes are linked to rhinovirus

U.S. Centers for Disease Control & Prevention - Serum testosterone levels in male rats are reduced by exposure to methoxychlor

U.S. Department of Health & Human Services - Vaccine liability update is presented

U.S. Environmental Protection Agency - Maine school district receives grant for clean school buses

U.S. Environmental Protection Agency - U.S. EPA reaches agreement with GNW Aluminum on clean-air violations

U.S. Food & Drug Administration - U.S. FDA initiative helps expedite development of seasonal and pandemic flu vaccines

U.S. National Cancer Institute - Angiogenesis is mediated by Shp-1 expression

U.S. National Cancer Institute - Methyltransferase depletion therapy mediates growth arrest and apoptosis

U.S. National Cancer Institute - PAX-FKHR fusion protein breakpoint epitope induces CTL that lyse tumors

U.S. National Institute of Allergy & Infectious Diseases - Vaccinia and smallpox viruses were neutralized by monoclonal antibodies

U.S. National Institutes of Health - Symptomatic West Nile virus infection risk increased by CCR5 deficiency

Ullevaal University Hospital, Oslo - Studies describe new findings in cardiology research

Umea University - Defective CTLA-4 induction is controlled by gene(s) in Idd5.1 region in nonobese diabetics

Unilever, North America - Healthy beverage guidelines proposed by expert nutritional panel

Universidade Federal do Ceara - Antitumor activity of physalins B and D investigated

Universita Vita-Salute San Raffaele - Immunofluorimetric assay to detect urokinase receptor chemotactic epitope is developed

Universitatsklinikum Erlangen - Researchers provide details of new studies and findings in the area of imaging

Universite de Nice Sophia-Antipolis - Warm ischemia-reperfusion injury is decreased by tacrolimus in steatotic rat liver

University Children's Hospital, Essen - Patients with cerebral arteriovenous malformations have high VEGF levels

University Clinics, Erlangen - Genetic association between endometriosis and DNA polymorphisms was evaluated

University College London - Promoting awareness of mouth cancer in Great Britain recommended

University Hospital, Birmingham - Researchers report details of new studies and findings in the area of environmental health

University of Adelaide - Link between common chromosomal fragile sites and cancer studied

University of Amsterdam - HIV-1 RNA helps guide patient selection for HAART in resource-poor settings

University of Athens - Fetal abnormalities may be detected with detailed sonography early in low-risk pregnancies

University of Autonoma Barcelona - Diet-induced insulin resistance and obesity susceptibility is mediated by PEPCK overexpression

University of Barcelona - Spanish Gaucher disease linked to nonsense-mediated mRNA decay in mutant alleles

University of Birmingham - Hepatocellular carcinoma development is associated with serum proteome changes

University of Bochum - Recombinant vectors enable the transduction of pancreatic and colon carcinoma

University of Bonn - Fungal infections can be treated efficaciously with itraconazole

University of British Columbia -  Ginkgo biloba modulates enzyme activity in rat hepatocytes

University of British Columbia - Cardiac lipoprotein lipase influence on diabetic heart disease is reviewed

University of British Columbia - Chronic hypersensitivity pneumonitis closely mimics fibrotic usual interstitial pneumonia

University of Cagliari, Monserrato - Efficacy of L-carnitine in cancer patients undergoing anticancer therapy studied

University of California, Los Angeles - Breast cancer patients' trust in familial input for decision-making differs by ethnicity

University of California, Los Angeles - HIV RNA upregulation in latently infected cells occurs within 2 hours after stimulation

University of California, Los Angeles - Lung cancer prognosticated by infiltration by CD8+ T cells and CD4+ T cells

University of California, San Diego - CD40 and GITR ligands act as adjuvants for HIV DNA vaccines

University of California, San Diego - HIV infection risk independently associated with methamphetamine in pregnant women

University of California, San Francisco - RNA splicing and chromatin remodeling prominent processes for adult neurogenesis

University of California, San Francisco - Reports add new data to cardiology research

University of California, San Francisco - Same-day mobile HIV testing in community settings is acceptable in sub-Saharan Africa

University of Cambridge - Common allele variations in IL18 are unlikely to contribute to type 1 diabetes

University of Cambridge - Maternal glycemia during pregnancy linked to high birth weight and diabetes risk

University of Cantabria, Santander - Breast cancer treated with low doses of alpha particle irradiation

University of Chicago - HIV community outreach services decreased in outpatient substance abuse treatment programs

University of Chile - Liver injury involves hydroxylation and cytochrome content

University of Edinburgh - Trypanosomiasis prevalence in surrounding villages predicted by central point sampling

University of Florida - Ischemic heart disease therapy in women should cater to gender-specific differences

University of Glasgow - Exhaled ethane in lung cancer patients measured with laser spectroscopy

University of Glasgow - Findings describe new data in pneumococcal vaccines research

University of Groningen - Improved compliance of heart failure patients depends on knowledge and change of beliefs

University of Hamburg - Prostate cancer patients were treated by sabarubicin

University of Helsinki - Chitosan does not increase drug availability in products when included in formulations

University of Houston - Antimicrobial agents' effect on heterogeneous microbial populations modeled

University of Illinois - Hydrogen sulfide implicated as a genotoxic agent

University of Ioannina - Cancer treatment options during pregnancy were the focus of review

University of Iowa - ACE inhibitor or angiotensin II receptor antagonist attenuates diabetic neuropathy

University of Kentucky - Researchers report details of new studies and findings in the area of prostate cancer

University of Kuopio - Reports advance knowledge in osteoporosis research

University of London Kings College - HIV-1 non-B subtype transmission continues in the U.K.

University of London St. Georges Hospital - Use of transrectal ultrasound-guided prostate biopsy to diagnose prostate cancer reviewed

University of Lund Hospital - Findings in bladder cancer provide new insights

University of Lund Hospital - Scintigraphically quantified ischemia correlates with summed ST deviation during coronary occlusion

University of Lyon 1 - HTLV-2b replication higher in endemically versus epidemically acquired infections

University of Maastricht - TUB is a novel candidate gene influencing body weight in humans

University of Manitoba - Herceptin sensitizes ErbB2-overexpressing cells to apoptosis

University of Medicine & Dentistry of New Jersey - Incidence of BRCA1/BRCA2 mutations in breast cancer patients varies by ethnicity

University of Miami - Focal dystonia benefits from treatment with botulinum toxin

University of Michigan - Women's high heart-surgery death rate may be due to infection

University of Michigan Hospitals - Cavotricuspid isthmus-dependent atrial flutter after left atrial ablation often shows atypical ECG

University of Milan - Endometriosis treatment strategies are reviewed for efficacy and safety

University of Munich - Plaque variety in proximal coronary system is detected by 64-slice computed tomography

University of Newcastle upon Tyne - Complete donor chimerism associated with prior acute cutaneous graft-versus-host disease

University of North Carolina - New findings in cancer therapy described

University of Oporto - Cleft lip/palate linked to CDH1/E-cadherin mutations in families with gastric cancer

University of Osaka Prefecture - Embryonic stem-like cells from canine blastocytes isolated and characterized

University of Oslo - CARDIA study indicates oxidative stress generated by adipose tissue lowers carotenoid levels

University of Ottawa - Eyes with retinal ischemia improve after receiving XIAP gene therapy

University of Padua - Aldosterone excess has a negative impact on glucose metabolism

University of Palermo - Frequency of additional cancers in patients with splenic marginal zone lymphoma assessed

University of Paris South - Intestinal barrier is modulated by miltefosine in the treatment of leishmaniasis

University of Pennsylvania - Myocardial infarct substrate can be localized by dynamic substrate mapping

University of Pennsylvania - No increased cardiovascular risk if mildly underactive thyroid left untreated

University of Pittsburgh - Overeating among overweight youth linked various eating disorder attitudes and behaviors

University of Regensburg - HBV surface antigen T and B cell memory triggers B cell antibody production

University of Santa Cristina Hospital, Madrid - Chronic hepatitis C therapy is associated with a sustained virological response

University of Santiago de Compostela - Effect of antioxidant vitamins on reducing risk of lung cancer investigated

University of Sao Paulo State - Recent findings in anesthesia provide new insights

University of South Florida - Chemotherapy-p53 cancer vaccine combination induces small cell lung cancer immune response

University of Southampton - Alzheimer disease-related cognitive impairment delayed by cholinesterase inhibitors

University of Southern Denmark - Protein kinase CK2 subunits are positive regulators of AKT kinase

University of Sydney - Hepatocyte-bone marrow cell fusion is driven by immune-mediated hepatitis

University of Sydney - Persistent fasting hyperglycemia in GDM pregnancy predicts diabetes mellitus development

University of Tennessee - High glucose increases insulin receptor expression and insulin-signaling pathway activity

University of Thessalia - Termination of luteinizing hormone surge may be regulated by ovarian factors

University of Thessaly, Larisa - Microsatellite instability at MEN1 locus implicated in lung carcinoid tumors

University of Tokyo - Vascular disorders may profit from sphingosine-1-phosphate therapy

University of Tsukuba - Hemoglobin reduction is associated with the use of erythrocyte ribavirin

University of Turin - Researchers' findings advance oncology research

University of Udine - Selecting patients in need of locoregional control of squamous cell carcinoma discussed

University of Utrecht - Researchers' data advance lung cancer research

University of Vermont - Insulin sensitivity may worsen in women using hormone replacement therapy

University of Vermont - Substance use disorders had better outcomes with the use of voucher-based reinforcement therapy

University of Western Australia - IL6/MHC gene mutations related to CD4 recovery in patients with stable virologic response

University of Wisconsin - Researchers' findings advance HIV/AIDS vaccines research

University of Witwatersrand, Johannesburg - Hepatitis B and C viral interaction may have a role in hepatocellular carcinogenesis

University of Zurich - Influenza vaccination coverage rates in France are reported

University of the Sacred Heart, Rome - Level of exposure to N-nitrosamines in rubber-manufacturing industry analyzed

University of the Sciences in Philadelphia - Antidepressant alterations in the mesocorticolimbic brain may improve behavior

Wake Forest University Baptist Medical Center, Winston-Salem - Criterion for diagnosing child abuse not always accurate

Weill Medical College of Cornell University, New York - Data advance knowledge in statins research

WellBound - WellBound study shows 42% of patients prefer home dialysis therapies when combined with education

West Virginia University, Morgantown - Adult willingness to be vaccinated against shigella varies throughout Asia

Whitehead Institute of Biomedical Research, Cambridge - Hematopoietic stem cell expansion ex vivo stimulated by angiopoietin-like proteins

Wilmer Eye Institute, Baltimore - Researchers publish new studies and findings in the area of ophthalmology

World Health Organization - Preeclampsia management may be enhanced with systemic literature search approach

Xencor, Inc. - HLA typing of MS patients may help identify patients for alternative therapies

Xuzhou Medical College - Recent studies add new data to ischemia research

Yale University - Frailty in elderly may be prevented or reversed if addressed early

Yale University - HIV serostatus disclosure higher among current partners than past partnerships

Yale University - Need to motivate fruit and vegetable intake among callers to Cancer Information Service proposed

Yale University - Study of early estrogen's effect on heart disease similar to WHI findings