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Chinese Academy of Medical Sciences, People's Republic of China

Zinc finger gene functions in erythroid and megakaryocytic differentiation

Published in Physician Law Weekly, July 26th, 2006

According to a study from the People's Republic of China, a novel zinc finger protein (HZF1) gene functions in erythroid and megakaryocytic differentiation of K562 cells.

"A novel zinc finger protein (HZF1) gene was identified and characterized by screening a human bone marrow cDNA library, using a new expression sequence tag probe that contains sequences encoding zinc finger motifs. There are at least three transcripts that may result from different splicing of the pre-mRNA, but the differences among them are only involved in 50 non-translation region of HZF1 mRNA," wrote H. Peng and colleagues, Chinese Academy of Medical Sciences.

"HZF1 gene...

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