National Institutes of Health, U.S.

Findings from the United States advance knowledge in HIV/AIDS research

Published in Physician Law Weekly, August 23rd, 2006

Reports from the United States highlight recent research in HIV/AIDS.

Study 1: Monomeric APOBEC3G is catalytically active and has anti-HIV activity.

According to a study from the United States, "APOBEC3G (APO3G) is a cytidine deaminase that restricts replication of vif-defective human immunodeficiency virus type 1 (HIV-1). Like other members of the cellular deaminase family, APO3G has the propensity to form homo-multimers."

"In the current study," wrote S. Opi and colleagues at the U.S. National Institutes of Health, "we investigated the functional determinants for multimerization of human APO3G and studied the role of APO3G...

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Source: Physician Law Weekly (2006-08-23)

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