University Hospital Bern, Bern, Switzerland

New findings from the United States and Japan in the area of apoptosis detailed

Published in Physician Law Weekly, October 4th, 2006

Data on apoptosis are outlined in reports from the United States and Japan.

Study 1: Lung cancer apoptosis was linked to the upregulation of death receptors 4 (DR4) and 5 (DR5).

According to recent research from Switzerland, "Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (Apo2L/TRAIL) belongs to the TNF family known to transduce their death signals via cell membrane receptors. Because it has been shown that Apo2L/TRAIL induces apoptosis in tumor cells without or little toxicity to normal cells, this cytokine became of special interest for cancer research. Unfortunately, cancer cells are often resistant to Apo2L/TRAIL-induced...

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Source: Physician Law Weekly (2006-10-04)

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