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Alzheimer Disease

Dosing commenced in Phase IIa trial of PBT2 in early Alzheimer patients

Published in Physician Law Weekly, January 17th, 2007

Prana Biotechnology Limited (PRAN; PBT) announced that dosing has commenced in its Phase IIa clinical trial of PBT2 in patients with early Alzheimer disease.

The PBT2-201-Euro trial is being conducted in seven centers throughout Sweden and will focus on exploring the safety and tolerability of PBT2, Prana's proprietary lead compound, and its effects on the mechanism and progression of the disease, investigating both central and peripheral biomarkers of Alzheimer disease as well as cognition.

The principal investigator for the trial is Professor Lars Lannfelt, MD, PhD, of the department of Public Health/Geriatrics at Uppsala University. Lannfelt and...

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