Interstitial Lung Disease

University of Ulsan reports research in interstitial lung disease

Published in Physician Law Weekly, June 25th, 2008

"Matrix metalloproteinase (MMP)-7 was reported to be a key molecule in the pathogenesis of idiopathic pulmonary fibrosis (IPF) based on the result of microarray analysis and knockout mice. However, the role of MMP-7 has not been determined in other types of idiopathic interstitial pneumonia (HP)," investigators in Seoul, South Korea report.

"The aim of this study was to investigate the role of MMP-7 in IIP by comparing its expression in usual interstitial pneumonia (UIP) and cryptogenic organizing pneumonia (COP). Levels of MMP and tissue inhibitors of metalloproteinase in BAL fluid and their expression on lung tissues were compared between normal control subjects (n =...

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Source: Physician Law Weekly (2008-06-25)

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