HSV-1

Nerve Growth Factor-Inducible Cellular Activity is Characterized

Published in Proteomics Weekly, November 2nd, 1998

In herpes simples virus type 1, NGF/FGF-induced n212-complementing activity may be responsible for initiation of viral gene expression during reactivation from neuronal latency when no ICPO is present.

Herpes simplex virus type 1 (HSV-1) ICPO is necessary for efficient viral gene expression during lytic infection, particularly at low multiplicities.

A series of cellular activities that can substitute for ICPO has been identified. This suggests that when ICPO activity is limiting, these activities can substitute for ICPO to activate viral gene expression. The cellular activities may be especially important during reactivation of HSV from...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Proteomics Weekly

Source: Proteomics Weekly (1998-11-02)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry