Published in Proteomics Weekly, December 21st, 1998
Reactivation of varicella herpes virus (VHV), latent in individuals who have previously suffered varicella, gives rise to herpes zoster and in some cases leads to a sequela of post-herpetic neuritis with severe pain which is refractory to analgesics.
Many different antiviral agents have been tried without achieving satisfactory results. Of all the antiviral agents employed, acyclovir has been the most successful in reducing post-herpetic pain. However acyclovir has not been as reliable as interferon alpha (IFN-(alpha)).
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