Proteomics Weekly
Susan Hasty, Publisher
Table of Contents . . . February 10th, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Proteomics Weekly | Other Publications
Ataxia Telangiectasia - Effects of rare, devastating disease linked to shrinking of cells' telomeres
Molecular Biology - Scientists focus on single molecules for first time
Alzheimer Disease - 22R-hydroxycholesterol protects from beta-amyloid peptide's cytotoxicity
Alzheimer Disease - Improved thioflavin-T derivative can label beta-amyloid plaque in vivo
Antibodies - Purification of serum polyclonal antibody using unique synthetic peptide column
Neuropathogenesis - HIV infected cell's virotoxins produce continuous cell loss and dementia
Alzheimer Disease - Altered G(Q/11) and RGS4 protein levels may affect muscarinic receptor system
Alzheimer Disease - Amyloid beta-peptide disrupts neural stem cell differentiation
Amyotrophic Lateral Sclerosis - Histidine residues oxidation induces superoxide dismutase misfolding/aggregation
Antioxidants - Green tea components are neuroprotective and may even prevent CVA
Apoptosis - Oxidative stress induces modulation of tau phosphorylation in oligodendrocytes
Canavan Disease - Aspartoacylase is restricted to myelin synthesizing cells in normal brain
Cell Biology - Deadly coral toxin exposes ion pump's deepest secret
Cell Proliferation - Endoplasmic reticulum-located PRL-1 involved in normal mitotic spindle operation
Cerebral Ischemia - Expression of cyclooxygenase-2, 5-lipoxygenase is upregulated in foci in humans
Collaborations - RiboTargets joins Partnership for Structural Biology at European facility
Creutzfeldt-Jakob Disease - Dendritic cells and macrophages in vessel walls also contain prion protein
Drug Development - Eli Lilly Canada enters collaborative research initiative in proteomics
Embryology - Many nicotinic receptors expressed differentially during spinal cord development
Gastroenterology - Dual processes depress interferon-induced STAT1 signaling in liver cells
Genetics and Genomics - Novel glutathione S-transferase from Cunninghamella elegans characterized
Genomics Database - U. of Pennsylvania licenses The Protein Atlas of the Human Genome database
HIV/AIDS Pathogenesis - Vpr protein docking to nuclear envelope mediated by interaction with the nucleoporin hCG1
Huntington Disease - An upstream open reading frame limits synthesis of huntingtin product
Immune Diagnostics - Improved generation of soluble HLA class I/peptide tetramers
Immune Evasion - Human papillomavirus oncoproteins E6 and E7 function to resist apoptosis
Infectious Disease - Source of diazoborine resistance in R. sphaeroides reported
Malaria Vaccine - Novel Plasmodium mutant enables evaluation of vaccine efficacy
Memory - Connection to human gene found
Molecular Biology - ETH researchers visualize the binding of proteins to the nuclear surface
Multiple Sclerosis - Tau protein concentrations in patient CSF is not a valid marker for disease
Neurodegeneration - Basal forebrain has dramatic loss of calcium binding protein with ageing
Neuroinflammation - Gemfibrozil, a lipid-lowering drug, inhibits the induction of iNOs in astrocytes
Neurology - Expression of Neuro-p24 demonstrates function in neurite extension
Neuronal Death - Inflammatory factors can upregulate microglial response factor (MRF)-1
Olfactory Bulb - Localization of zinc enriched neuronal somata
Organic Chemistry - Researcher explores new uses for nicotine and sea sponges
Parkinson Disease - Cytoplasmic aggregates of protein kinases found, also alter cell function
Parkinson Disease - Montreal Neurological Institute researcher receives grant of US$296,656
Parkinson Disease - Prostaglandin A(1) inhibits rotenone induced apoptosis in SH-SY5Y cells
Patents - Company to receive patent for proteomics research processes
Prion Diseases - Intercellular transfer of protein is a dependent, regulated process
Prion Diseases - There are two patterns of protein deposits in variant Creutzfeldt-Jakob disease
Proteomics - Altered expression of retinoblastoma protein-interacting zinc finger gene in leukemia
Receptor Studies - TGF-beta induced protein controlling cell adhesion also interacts with integrin
Stem Cell Research - M. tuberculosis induces differentiation of dendritic cells from bone marrow
Stem Cell Research - CD45 may play key role in erythoid differentiation
Stem Cell Research - Distal elements critical for human CD34 expression in vivo
Stem Cell Research - Growth inhibitors promote differentiation of insulin-producing tissue
Stem Cell Research - Mutant elastase causes cyclic and severe congenital neutropenia
Stem Cell Research - PDGF upregulates delayed rectifier current in oligodendroglial progenitors
Stem Cell Research - Transcription factor NFATc1 mediates RANKL signaling in osteoclast differentiation
Stem Cell Transplantation - Gelsolin levels predict idiopathic pneumonia
Transfusion Medicine - Protein A Sepharose treatment restores platelet concentrate efficacy in thrombasthenia
Tuberculosis Therapy - Mycobacterial trehalose-phosphate synthase may be therapeutic target
Tumorigenesis - Adenomatous polyposis gene regulates beta-catenin affecting cell differentiation
Type 1 Diabetes - Researchers pinpoint link between diabetes and nervous system autoimmunity
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