Proteomics Weekly

HIV/AIDS Therapy - Novel agents inhibit viral Vpr protein function

HIV/AIDS Vaccine -  Salmonella-based priming improves mucosal antiviral response

HIV/AIDS Vaccine - Effects of viral protein modifications on immunogenecity characterized

Human B-Cell Lymphoma - RC-K8 cells have multiple genetic alterations affecting Rel/NF-kappa B

Immune Cell Distribution - HIV-1 plasma viremia is shown to influence dendritic cell number and activity

Immunoglobulin M - Distribution of B cell types is regulated by the presence of polyclonal IgM

Immunomodulation - Chimera a novel alternative for preventing graft rejection

Infectious Disease -  Pseudomonas resistance protein Ohr characterized

Infectious Disease -  Toxoplasma gondii redox couple potential drug target

Infectious Disease -  mtrR promoter deletion not needed for N. gonorrhoeae drug resistance

Infectious Disease - New protein will help fight inflammation

Infectious Disease Diagnosis - Standard tests may miss H. influenzae extended-spectrum beta-lactamases

Inflammatory Response - Calcium can regulate GM-CSF transcription positively and negatively

Leukemia - Zinc-induced apoptosis requires caspase and p38(MAPK) activation

Leukemogenesis - Post-transcriptional RNA-binding shuttling proteins perform important role

Lung Cancer - Human erb-B-3 transgenic mouse model elucidates tumorigenesis mechanism

Lymphomas - Only aggressive subset has same amount of mRNA but decreased CHK2 expression

MHC Class I - Nonclassical HLA-G, of no known receptor, forms disulfide-linked dimers on cell

Malaria Pathogenesis - Age-dependent enhancement of IFN-gamma responses to liver stage antigen-1 T cell epitopes

Malaria Research - Second P. falciparum proliferating cell nuclear antigen found

Molecular Function - Stereoenantiomers of lysophosphatidic acid induce proliferation or apoptosis

Molecular Modeling - Possible oncogenic switch found by studying two transmembrane domains of erbB2

Myeloma - Increased activation of N-ras and K-ras pools induced by increases in IL-6

Neurodegenerative Disease - Mutated gene normally manages protein folding

Ovariectomy - Increased IL-7 is related to postoperative bone loss

Parkinson Disease - Discovery gives insight to neurological disorders

Protein Structure - Common themes in protein kinases from diverse organisms

Proteomics - Protein microarray technology may help biological system understanding

RNA Metabolism - Processing elements associate with multiple brain proteins

Skin Inflammation - Substance P and IFN-gamma together enhance keratinocyte production of IP-10

Stem Cell Research - Neurogenin3 needed endocrine cell fate specification in intestinal and gastric epithelium

Stem Cell Research - Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1

Systemic Lupus Erythematosus - Autoimmunity possibly originates from stress and altered polyamine expression

Tissue Culture - A 3D tissue culture structure alters fibroblast response to TGF-beta 1

Urothelial Cancer - MAP-kinase pathways for normal cell proliferation are used less by cancer cells

West Nile Fever - Viral capsid protein induces inflammation through apoptotic pathway