Published in Proteomics Weekly, March 3rd, 2003
"Plasmodium sporozoites are transmitted through the bite of infected mosquitoes and first invade the liver of the mammalian host, as an obligatory step of the life cycle of the malaria parasite," explained O. Silvie and coauthors at the University of Paris. "Within hepatocytes, Plasmodium sporozoites reside in a membrane-bound vacuole, where they differentiate into exoerythrocytic forms and merozoites that subsequently infect erythrocytes and cause the malaria disease."
"Plasmodium sporozoite targeting to the liver is mediated by the...
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