Malaria Pathogenesis
Hepatocyte CD81 expression needed for plasmodial sporozoite infectivity
Published in Proteomics Weekly, March 3rd, 2003
"Plasmodium sporozoites are transmitted through the bite of infected mosquitoes and first invade the liver of the mammalian host, as an obligatory step of the life cycle of the malaria parasite," explained O. Silvie and coauthors at the University of Paris. "Within hepatocytes, Plasmodium sporozoites reside in a membrane-bound vacuole, where they differentiate into exoerythrocytic forms and merozoites that subsequently infect erythrocytes and cause the malaria disease."
"Plasmodium sporozoite targeting to the liver is mediated by the...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Proteomics Weekly
Source: Proteomics Weekly (2003-03-03)
More Articles from Proteomics Weekly
- Antiviral Defenses
Three IFN-lambdas act through a distinct class II cytokine receptor complex - Cervical Cancer
Papillomavirus' E6 and E7 proteins differentially protect from cell apoptosis - Cellular Transformation
Induction of apoptosis-modulating p202 occurs, contributing to cell survival - HIV/AIDS Pathogenesis
Interleukin-15 overexpression prevents murine AIDS - Hepatic Fibrosis
Activated stellate cells express TRAIL and can be eliminated differentially - Proteomics
New mechanism of collagen I recognized in study of cell organization - More from this issue of Proteomics Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
