Susan Hasty, Publisher
Table of Contents . . . March 31st, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Proteomics Weekly | Other Publications
Glucose Regulation - Zinc appears to play role in homeostasis
Rhabdomyosarcoma - Gene that drives apoptosis also plays key role in development of skeletal muscle
Cell Biology - USC researchers uncover age discrimination in secretory cells
HIV/AIDS Proteomics - Alternative gp120 V3 loop conformations mimic chemokine beta hairpins
Laboratory Techniques - Scientists track cancer in 3-D, one cell at a time
Research Trends - Reports examine current and future state of proteomics
Virology - Pseudocowpox virus contains a homolog of vascular endothelial growth factor
Adenovirus - A bifunctional ligand protein modifies adenoviral tropism
Allergy Medicine - Chemokine receptors play a key role in inflammatory cell recruitment
Alzheimer Disease - Columbia researchers identify possible new culprit in plaque formation
Apo E Polymorphism - Apolipoprotein E detection in CSF and serum yield the same results
Apoptosis - Granzyme A cleaves the oxidative repair protein Ape1, enhancing cell death
Axonal Degeneration - Blockers of sodium and calcium entry protect axons from nitric oxide
B Cell Activation - A new membrane associated adaptor molecule, LAB, is similar to LAT
Biosequencing - New database of nucleotide and amino acid sequences launched
Blood Brain Barrier - Activated T cells directly affect endothelial cells in inflammation
Brain Damage - High-fat diet may protect newborn brain cells from seizure damage, study says
Breast Cancer - Metastasis and tumor growth suppression achieved with propolis in mouse model
Cell Adhesion/Migration - Recombinant laminin-5 forms reveal two domains involved in normal activity
Cell Biology - Role of heterotrimeric G-protein signaling in plant cell proliferation identified
Cell Cycle - Nuclear phosphatase and tensin homologue is associated with G0-G1
Chronic Hepatitis C - Hepatitis C virus NS2 protein inhibits cellular and hepatitis B gene expression
Cirrhosis - Rhodiola sachalinensis extract appears to protect from chemical liver injury
Cutaneous T Cell Disease - Endothelial cells induce T-cell chemokine CCL21 in autoimmune patients
Dermatology - A protein cluster links UVB and the induction of growth factor in skin cells
Drug Design - Optimization of therapeutics can be accomplished by directed evolution
Endodontics - Mu-opioid receptors are found in human dental pulp
Environmental Risk - Recent orchidopexy rates don't support endocrine disruptor hypothesis
Gliomal Cell Surface - Stripping proteoglycans of sulfation leads to adhesional and migrational changes
HIV/AIDS Pathogenesis - Syndecan plays key role
HIV/AIDS Proteomics - PDI-mediated reduction of gp120 disulfide bonds needed for virus/cell fusion
HIV/AIDS Therapy - Anti-glycoprotein 41 immunotoxins effective in mice
HIV/AIDS Therapy - Nelfinavir inhibits lymphocyte P-glycoprotein activity
HIV/AIDS Women's Health - C-reactive protein levels predict mortality risk
Helicobacter Pylori - A novel apoptosis-inducing protein complex is related to pathogenesis
Hematology - Strong static magnetic field had no effect on normal lymphocytes
Hematopoiesis - An autocrine-paracrine loop potentiates megakaryocytic maturity through Flt1
Hepatic Metastasis - Interleukin-18 binding protein therapy can neutralize cancer adhesiveness
Hepatitis A Virus - Protein exchanges with hepatitis A virus cover different mechanisms
Hepatology - Cellular density and cell-cell contact mediate plasminogen in hepatocytes
Hyperalgesia - P38 MAP kinase is activated in ganglia and spinal cord postinflammation
Infectious Disease Therapy - The bactericidal agent gentamicin enhances phagocytized bacterial killing
Intestinal Inflammation - Pyrrolidinedithiocarbamate inhibits NF-kappa B and thus IL-8 production
Legionella Pneumophila - The PPIase site of the Mip protein is essential for infection in host
Lung Cancer - Downregulation of the tetraspanin CD9 appears to increase metastatic ability
Lung Cancer - Tumor-derived soluble factors enhance activated T cell apoptosis
Marfan Syndrome - Early miscues cause late problems in model of Marfan syndrome
Memory T Cells - NF-kappa B transcription factors are needed for differentiation
Mosquito-borne Disease - Novel Anopheles gambiae serpin isoforms may mark ookinete invasion
Multiple Sclerosis - Intrathecal IgM synthesis is an indicator of very poor prognosis
Myeloid Growth Suppression - New small unstable apoptotic protein has a different mechanism of action
Narcolepsy - The protein responsible for wakefulness, orexin, is lacking in narcolepsy
Nasopharyngeal Carcinoma - EBV+ cells suffered apoptosis after doxorubicin/BIM2001 combination
Nephrotoxins - The mycotoxin ochratoxin A is found in some Greek wines
Oncology - The binding protein CUGBP2 silences cyclooxygenase-2 expression
Pneumonia - Expression of Duffy antigen on alveolar septa is associated with infection
Prostate Cancer Marker - Cdc25B is an androgen receptor coactivator that is overexpressed
Rheumatoid Arthritis - B7-H1 autoantibodies react with antigen on T cells to induce apoptotic response
Salmonella Infection - Dendritic cells play a key role in immune protection
Sensory Neuropathy - Monoclonal IgM is bound to a trisulfated heparin disaccharide
Spinal Muscular Atrophy - Scientists discover possible new treatment for genetic diseases
Stem Cell Research - Intestinal EP2 receptors mediate prostaglandin effects
Stem Cell Research - Spermatocytes lacking PUF-8 protein revert to mitotic germ cells
Toxoplasmosis - Efficient expression of 3 antigens allows use for diagnostic assay
Transformation Marker - Morules with optically clear nuclei were found in an ovarian cancer
Transplant Medicine - Retinal precursor cells express functional neuronal receptors
Trypanosomiasis - NK-lysin and a shortened synthetic analog NK-2 are potent antiprotozoans
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