Proteomics Weekly

Hereditary Periodic Fever - TNF-receptor associated periodic syndrome may be treatable with TNF receptors

Immune Therapy - Cutaneous B-cell pseudolymphoma is a recurrent risk years after antigen therapy

Immunology - Kinetics, gene regulation in lymphocyte polarization to Th1 & Th2 cells studied

Immunology Database - MHCBN, available on the internet, has MHC binding and non-binding peptide data

Kawasaki Disease - Coronary artery inflammation is a high risk for babies with low serum albumin

Liver Disease - Nitric oxide may have cytoprotective effects on glucose deprived hepatocytes

Liver Surgery - Percentage of liver remaining is predictive of degree of hepatic function

Lyme Disease - Antibodies to VlsE IR6 can persist years after successful antibiotic treatment

Lymphocyte Research - ELISPOT is a very useful method for T cell epitope mapping

Malaria Enzymology - Plasmodial Rab GTPases characterized

Malaria Pathogenesis - Novel plasmodial gene family identified

Multiple Sclerosis - New discovery may provide insights

Muscle Cell Differentiation - LIM proteins paxillin and Hic-5 may be involved in human cell differentiation

Neurodegenerative Diseases - Nonepisodic autosomal dominant spinocerebellar ataxias have different mechanisms

Pemphigus Vulgaris - Neonatal skin blistering was induced by IgG4 autoantibodies to desmoglein 3

Peptic Ulcer Disease -  Helicobacter pylori vacuolating toxin is now expressible in E. coli

Prion Diseases - Clue to prion formation found, offers step toward treating puzzling diseases

Protein Purification - Method enables one-step metal-affinity purification of His-tagged proteins

Proteomics - Phosphatidic acid phosphatase 2b/VCIP regulates cell to cell interactions

Proteomics - Progress in immunoconjugate technology has revitalized the magic bullet concept

Psoriasis - The S100A7 or psoriasin gene is duplicated 5 times in humans

Pulmonary Tuberculosis - Osteopontin levels linked to disease severity

Skin Resurfacing - Faster reepithelialization occurs without laser char debridement

Staphylococcal Infection - Sigma factor SigB plays role in drug resistance

Stem Cell Research - Murine serpin 2A protein is intracellular and redox-sensitive

Stem Cell Research - Platelet-derived growth factor upregulates megakaryocytic transcription factors

Systemic Lupus Erythematosus - Anti-phospholipid syndrome patients have anti-plasminogen autoantibodies

T-Cell Activation - CD28 acts in 2 different ways, dependent on cis and trans conformation

Thyroid Disorders - Study of thyroxine transporter molecule shows how key hormone hitches a lift round body

Tuberculosis Immunology - Complex chemokine responses underlie bone degeneration

Tuberculosis Pathogenesis - Cytokine release by infected monocytes mediated by MAPK pathways

Tuberculosis Proteomics - Rv2579 protein is haloalkane dehalogenase

Tuberculosis Proteomics - Rv3133c/DosR is a transcription factor involved in infection latency

Umbilical Cord Blood - Fibrinogen promotes megakaryocytopoiesis, but not thrombopoiesis