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Guillain-Barre Syndrome

Relapse following IVIg therapy isn't related to antiganglioside antibody titer

Published in Proteomics Weekly, August 18th, 2003

Anti-ganglioside antibody is not responsible for relapse in Guillain-Barre syndrome treated with plasmapheresis and IVIg.

According to a study from Japan, "Since plasma exchange (PE) and intravenous immunoglobulin (IVIg) have been widely used in treatment for Guillain-Barre syndrome (GBS), early relapse and treatment-related fluctuation have been a potential problem, but little is known about the mechanism of relapse and fluctuation. We describe a patient who had GBS with treatment-related fluctuation.

"A 37-year-old Japanese man exhibited acute distal-dominant weakness in upper limbs after upper respiratory infection. His cranial nerve system was...

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