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Oncology

Somatostatin analogues may be of value for treating laryngeal malignancy

Published in Proteomics Weekly, September 15th, 2003

Somatostatin analogues may be of value for treating laryngeal malignancy.

According to published research from England, "the role of chemotherapy in squamous cell carcinoma of the larynx has not been clearly defined. Whilst toxic chemotherapy regimes may confer a marginal improvement in survival, surgery and radiotherapy remain the mainstay of treatment. Somatostatin is a naturally occurring peptide, which exerts antiproliferative and antiangiogenic effects via five membrane-bound receptor subtypes."

"The expression of somatostatin receptor subtypes (SSTRs) 1 and 2 was studied in benign, pre-malignant and malignant laryngeal specimens. Epithelial...

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