Diagnostics
A new sandwich immunoassay for prion detection is faster and more sensitive
Published in Proteomics Weekly, September 15th, 2003
According to a study from Germany, "The presence of pathogenic prion protein (PrP(Sc)) in lymphoid tissues of variant Creutzfeldt-Jakob disease (vCJD) patients raises questions as to whether prions may be present in bodily fluids as well. Currently, transgenic mice are highly sensitive in vivo tools for the study of prions in tissues or fluids containing high levels of normal prion protein (PrP(C)).
"We report here an in vitro assay with virtually equivalent sensitivity incorporating a capture antibody into a sandwich...
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Source: Proteomics Weekly (2003-09-15)
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