Genital Herpes

Antibodies to HSV-2 glycoprotein G are not always there during primary infection

Published in Proteomics Weekly, January 19th, 2004

Antibodies to herpes simplex virus type 2 (HSV-2) glycoprotein G are not always there during primary infection; various methods show a wide range of seroconversion times.

According to published research from the United States, "glycoprotein G-based ... HSV-2 enzyme-linked immunosorbent assays from Focus and Kalon were performed with specimens from 118 patients with culture-documented genital herpes episodes, and their results were compared.

"Sensitivity was 52% by Kalon and 86% by Focus for first HSV-2 episodes and 100% (for each of the 2 tests) for recurrent HSV-2," wrote R.A. Morrow and coauthors.

The researchers concluded: ...

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Source: Proteomics Weekly (2004-01-19)

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