Endocrinology

Gut peptides modulate pancreatic secretions

Published in Proteomics Weekly, February 2nd, 2004

Peptides originating in the gut are involved with the modulation of pancreatic secretions.

According to a study from Poland, "Exocrine pancreatic secretion, attributed initially to neural reflexes (nervism), was then found to depend also on enterohormones, especially secretin and cholecystokinin (CCK), released by the intestinal mucosa and believed to act via an endocrine pathway.

"Recently, CCK and other enterohormones were found to stimulate the pancreas by excitation of sensory nerves and by trigger of long vagovagal or ('brain-gut axis') enteropancreatic reflexes. Numerous neurotransmitters, such as acetylcholine, and certain neuropeptides, such...

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Source: Proteomics Weekly (2004-02-02)

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