Mental Health
Effects of imipramine on prefrontal cortex gene expression elucidated
Published in Proteomics Weekly, May 31st, 2004
In a recent study, scientists in Finland "investigated gene expression changes produced by acute and chronic daily treatment with a prototypical antidepressant, imipramine, using DNA microarrays.
"The analysis of similarities in gene expression patterns among functionally related genes revealed four expression profile cluster areas that showed a highly significant over-representation of several functional classes," reported J.E.A. Knuuttila and coauthors at the University of Helsinki.
"Genes encoding for proteins involved in cAMP metabolism,...
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Source: Proteomics Weekly (2004-05-31)
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