Proteomics Weekly

HIV/AIDS Research - Host factor Sam68 enhances HIV-1 RNA 3' end processing

Heart Transplantation - Improved antibody array identifies CPB-induced CD antigens

Hepatitis B Virus Therapy - Reverse transcriptase inhibitors treat woodchuck hepatitis virus

Hepatitis C - "Self-recovery" from liver infection linked to genes

Hepatitis C Virus - Fluorescent marker permits the visualization of HCV replication complexes

Hepatocellular Carcinoma - Raf-1 activation linked to pathogenesis

Hepatocellular Carcinoma - RhoC expression linked to poor prognosis

Hepatology - Proapoptotic effects of SAMe in HepG2 cells elucidated

Hormone Replacement Therapy - Estrogen modulates synthesis of osteoprotegerin and RANKL by megakaryocytes

Immunology - I-E^d-restricted T-cell epitope of E. coli membrane protein identified

Infertility - BubR1 protein insufficiency is associated with aging and infertility in mice

Inflammation - Wood smoke increases expression of two mucin genes in rat airways

Information Technology - Bioinformatics solution provider announces collaboration with Matrix Science

Interferon - Four resistance factors identified in interferon inhibitory activity

Leishmaniasis - Leishmaniasis transmission by sand flies enhanced by regurgitation of fPPG

Lipid Studies - Expression of lung uncoupling protein-2 mRNA modulated by caloric intake

Liver Transplantation - Isolated small intestinal segments support transplanted liver fragments

Lung Cancer - BRM/BRG1 expression has prognostic value in NSCLC

Lymphoma Therapy - Effects of anti-CD19 mAb on P-glycoprotein pump elucidated

Malaria - Molecular analysis of Plasmodium ovale variants reported

Malaria Vaccine - Small peptide induces complete protection against malaria

Mergers & Acquisitions - Gene expression company announces acquisition of Digital Gene Technologies

Metastasis - Syndecan-1 expression relocates during cancer progression

Microbiology - RRF disassembles the ribosomal complex independently of EF-G

Molecular Biology - Researchers map structure of anticancer molecule

Moraxella Vaccine - Outer membrane proteins of Moraxella catarrhalis characterized

Muscular Dystrophy - Forced dystrophin expression improves calcium handling in muscle cells

Mutagenesis - Alkaloid riddelliine induces mutations in liver cII gene of Big Blue rats

Myocardial Infarction - AMPK protein plays important protective role during and after heart attack

Neuroscience - Guinea pig 5-ht_5A receptor characterized

Neuroscience - Interaction between NO and NAChR plays role in sleep/wake cycle

Neuroscience - Mutation at position 129 of prion protein doesn't affect its cellular form

Neuroscience - Oligonucleotide decoys modulate trauma response in the nervous system

Neuroscience - Regional COX-3 mRNA distribution determined in rat CNS

Neuroscience - S100B overexpression augments ischemic neurological damage

Newborn Health - Results published on biomarker for diagnosing preterm birth-associated infection

Newborn Screening - New England Newborn Screening Program expands services in Pennsylvania

Obesity Pathogenesis - Expression of agouti-related protein mRNA down-regulated in obese mice

Obesity Pathogenesis - Ghrelin expression reduced in stomachs of obese mice

Obesity Pathogenesis - Ghrelin plays role in obesity development outside of leptin signaling

Oncogenesis - Cyclooxygenase 2 is an important regulator of lung cancer pathogenesis

Oncogenesis - Hepatitis B virus x protein halts apolipoprotein B production in liver cells

Oncogenesis - Nestin overexpression mediates the malignant potential of neuroblastoma

Oncology - Sil overexpression linked to heightened mitotic activity in tumors

Ovarian Cancer - Expression of EBAG9/RCAS1 is associated with advanced disease

Parasitology - Gender-based differences in S. japonicum gene expression identified

Parkinson Disease - Differential gene expression identified in UCH-L1-deficient mice

Personnel - HEMOLINK maker announces appointment of Edward Lane to board

Poxvirus Vaccine - Understanding of poxvirus pathogenesis advanced by deleting viral genes

Prion Diseases - Amyloid-targeting PET ligand facilitates diagnosis

Prion Diseases - Proteins act as stepping stones in evolution

Proteomics - DNA-directed immobilization improves antibody microarray performance

Proteomics - Database of protein domains and ligands developed

Proteomics - Glycosylation system is important for attachment to epithelial cells

Proteomics - High-throughput parallel functional protein microarray system developed

Proteomics - Insights reported from global structural genomics target lists

Proteomics - InterWeaver web server aids biologists in discovery of protein interactions

Proteomics - Life sciences company introduces three new protein purification kits

Proteomics - PEG-coated Si(111) surface improves protein immobilization

Proteomics - Protein therapeutics company reports second quarter financial results

Proteomics - SC15 protein mediates formation of aerial hyphae and attachment

Proteomics - Ski is a corepressor for Smad4

Proteomics - Surface plasmon resonance imaging is used for protein expression analysis

Proteomics - Web server generates peptide sequences with extended conformation

Proteomics - Web-based tool aids protein structure searches

Pulmonary Medicine - Secretory leukoprotease inhibitor can be targeted for treating lung cancer

Receptor Studies - Soluble growth factor receptor is a major biomarker for angiogenesis

Renal Disease - The antiangiogenic peptide tumstatin reverses early diabetic nephropathy

Reproductive Biology - IGF-I overexpression causes fetal loss during placentation in mice

Retinitis Pigmentosa - New clues to hereditary blinding disease found

SARS - Researcher uses supercomputer to model a SARS viral enzyme

Streptococcus Vaccine - Vaccines of Streptococcus polysaccharides and T cell epitope developed

Synovial Sarcoma - Novel PDZK4 gene upregulated in SS tumor cells

Vaccine Delivery - Drug delivery systems reviewed

Vaccinia Virus - Sequence-independent acylation of vaccinia virus inclusion protein reported

Vector Development - Photochemical transfection enhances the cytotoxicity of suicide gene therapy

Vectors - X marks the spot: Vector insertion is viral-specific

Viral Genomics and Genetics - Dam inactivation reduces Haemophilus influenzae virulence

Viral Proteomics - Hepatitis E virus protein ushers liver-specific precursor protein from cells

Wound Care - Matrix metalloproteinase activity is fundamental to proper wound healing