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Immunology

The selective COX-2 inhibitor DFU staunches tumor growth in mice

Published in Proteomics Weekly, September 20th, 2004

The selective COX-2 inhibitor DFU staunches tumor growth in mice.

According to recent research published in the journal Oncology Reports, "cyclooxygenase-2 (COX-2) inhibitors are regarded as potentially important in strategies for cancer treatment. However, the precise mechanisms of these anti-inflammatory drugs as anticancer therapy are still unknown. In this study, we examined the effect of DFU both in vitro on MCF-7 cell growth, as well as in vivo on tumor growth produced by MCF-7 cell injection in mice."

"DFU has growth inhibitory effects on tumor growth in mice compared to the control group. We examined the tumor tissues for apoptosis and...

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