Ovarian Cancer

Novel target found for detecting ovarian cancer in blood

Published in Proteomics Weekly, October 4th, 2004

Scientists have discovered a new way to detect ovarian cancer in the blood.

Reporting in the September 15, 2004, issue of Cancer Research, Fox Chase Cancer Center, Philadelphia, researchers explain that the new method targets hypermethylation, one mechanism used by cancer cells to turn off genes that protect against tumor development.

When these tumor-suppressor genes are inactivated by hypermethylation, they cannot do their job, which then allows cancer cells to develop. This research marks the first time hypermethylation has been examined for the detection of ovarian cancer.

Fox Chase molecular biologist Paul Cairns, PhD,...

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Source: Proteomics Weekly (2004-10-04)

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