Proteomics Weekly

HIV/AIDS Research - APOBEC3F is suppressed by HIV-1 and HIV-2 Vif proteins

HIV/AIDS Research - Human cytidine deaminase APOBEC3G is a broad antiviral enzyme

HIV/AIDS Therapy - Antifungal peptides inhibit HIV-1 reverse transcriptase

Hematology - VEGF receptors collaborate in the differentiation of bone marrow progenitors

Hematopoiesis - B-cell linker protein is essential for PLC-gamma2-induced Ca2+ influx

Hepatocellular Carcinoma - Reduced CYP2E1 expression associated with poor prognosis

Immunodeficiency Disorder - Flow cytometry confirms Wiskott-Aldrich syndrome in youth with thrombocytopenia

Immunology - Factor VIII DNA transfer stimulates anti-transgene antibodies in mice

Influenza Vaccine - Method to predict antigenic variants of influenza viruses developed

Information Technology - Provider of enterprise bioinformatics solutions announces new solutions

Insulin - Two LysB29 specifically labeled insulin derivatives characterized

Leptin Studies - Lipopolysaccharide affects leptin transport across blood-brain barrier

Lipid Studies - Isocaloric PUFA diet enhances lipid uptake and weight gain

Lung Cancer - The enzyme regulator RECK opposes non-small cell lung cancer angiogenesis

Lung Cancer - Wnt-2 inhibition induces apoptosis in NSCLC cells

Malaria Vaccine - Analogue of epitope from malaria vaccine protein characterized

Malaria Vaccine - Conserved region of P. falciparum targeted by antibodies identified

Malaria Vaccine - Long-term T-cell responses induced by Plasmodium peptides

Malaria Vaccine - PfEMP1-DBL1 alpha antibodies protect Plasmodium falciparum

Melanoma - Heightened Jab1 expression linked to metastasis

Melanoma Vaccine - Antibodies elicit antigen-specific T cells in melanoma patients

Metastases - Angiogenic factors encourage the metastatic potential of prostate cancer

Molecular Biology - The transcription factor LBP-1a is critical for extraembryonic angiogenesis

Multiple Sclerosis - Link found between ancient viral protein and MS

Muscular Dystrophy - Stimulating the production of utrophin protects mice from muscle wasting

Myeloproliferative Disease - Experimental drug shown to block mutant protein causing blood disease

Nanotechnology - Cancer institute announces commitment to nanotechnology for cancer research

Nanotechnology - Grant award to fund NanoReader device to target detection of whole viruses

Nausea - Helsinn enters agreement for Palonosetron in the U.K.

Neovascularization - ERK and p38 MAP kinases serve different functions during tube formation

Neurology - Secretin and its receptor are expressed widely and early in the rodent brain

Neuroscience - Company announces availability of new bioapplication software module

Neuroscience - Function of potassium channel TREK-1 clarified

Neuroscience - Herpes simplex virus driven gene therapy provides neuroprotection to mice

Neuroscience - Pacemaker activity is regulated by glycine receptor ligands in hydra

Oncology - CD9-mediated p46 Shc activation triggers apoptosis in tumor cells

Pancreatic Islets - Vanilloid expressed in pancreatic cells modulates insulin secretion

Personnel - Katrine Bosley named VP of company developing protein antagonist therapeutics

Personnel - Pharmaceutical company announces management change and promotions

Pharmacology - CYP1A2 plays key role in hepatic metabolism of trans-resveratrol

Pharmacology - CYP3A5 has limited role in hepatic 6beta-hydroxylation of testosterone

Pneumococcal Vaccine - Antibodies against pneumococcal proteins developed

Pneumonia - Staphylococcal protein A appears to inflame the lungs

Protein Synthesis - Heparin dose-dependently modulates protein synthesis

Protein Synthesis - Serum-free large-scale transfection produces bigger protein yields

Proteomics - Human and chimpanzee brains share many regional gene expression patterns

Proteomics - Monoclonal antibodies used to isolate oxidative phosphorylation complexes

Proteomics - NO-induced BNIP3 expression induces apoptosis in macrophages

Proteomics - Newcastle disease virus P gene doesn't encode accessory X protein

Proteomics - Novel polymeric coating may improve protein microarray performance

Proteomics - Novel protein distinguishes CD8 cells from other lymphocytes

Proteomics - Pharma company announces collaboration expansion with Kirin Brewery

Proteomics - Review surveys use of lipid bilayer models in peptide and protein simulations

Proteomics Research - Research start developing a protein infrared spectra databank

Pulmonary Medicine - CD117 immunoreactivity identifies patients with highly aggressive lung cancers

Rectal Cancer - Radio-resistance-related proteins in rectal cancer reviewed

Reproductive Biology - Cyclic mechanical stretch augments IL-8 and MCP-3 production in cervical cells

Reproductive Biology - Study findings suggest physiological roles for Ang-(1-7) and ACE2 in pregnancy

Research Technology - Demand for research instruments grows as government backs research, study shows

Respiratory Syncytial Virus - Recombinant respiratory syncytial virus with deletion characterized

Retrovirus Research - SIV Vpr/Vpx kill bystander noninfected CD4+ cells by induction of apoptosis

Rheumatoid Arthritis - Agent decreases production of destructive antibodies in mice

SARS Vaccine - Neutralizing monoclonal antibodies to SARS-coronavirus characterized

Salivary Gland Cancer - Phenotypic classification system developed

Sepsis - Inducible NOS plays key role in pulmonary neutrophil infiltration

Stem Cell Research - Early Trx/Ccl-2 expression favors increased survival potential of B cells

Stem Cell Research - Multilineage inducible cells are ideal candidates for cellular therapies

Streptococcus Vaccine -  Streptococcus mutans epitope recognized by antibody 6-11A described

Streptococcus Vaccine - Sialic acid O-acetylation in group B Streptococcus characterized

Thrombosis - Role of vitronectin in clot formation clarified

Transgene Expression - Cytosolic soluble proteins boost DNA release from nonviral gene carriers

Vaccine Development - Dimeric gonadotrophin-releasing hormone vaccines elicit immune response

Vaccine Development - Outer membrane vesicles production in Gram-negative bacteria improved

Vaccinia Virus - A13 phosphoprotein required for assembly of mature vaccinia virions

Viral Proteomics - Zinc triggers the assembly of hepatitis B virus capsid protein

Virology - Murine sex differences in genomic response to Seoul virus identified

Virology - Study of capsid proteins may shed light on retroviruses